Formula ^4,5

Omeprazole suspension 2mg/mL

 

Omeprazole Capsules 20mg	5
Sodium Bicarbonate Solution 8.4%	50	mL
Method Empty the contents of the capsules into a mortar and triturate gently with about 10mL of the sodium bicarbonate solution.  A smooth paste will be formed when the enteric coating has dissolved and the drug is dispersed.  Make to volume.
Expiry:  15 days under refrigeration. This is a conservative expiry date.  Studies indicate chemical stability for longer periods but stability under in-use conditions was not assessed.
Stability:   14 days at 24°C;  30 days at 5°C.^4
Storage:  Omeprazole is light sensitive and storage in amber plastic or glass containers is recommended.  A colour change (to orange or black) may occur on exposure to light.^6  The suspension can also be stored in plastic syringes.^4
SHAKE THE BOTTLE  This is important as omeprazole is incompletely dissolved and partly in suspension.^5